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AEROCORT INHALER: PRESCRIBING INFORMATION
Each actuation delivers:
Beclomethasone Dipropionate 50 mcg
Levosalbutamol Sulphate (Levalbuterol Sulfate) equivalent to levosalbutamol 50 mcg
Suspended in propellant HFA-134a q.s.
Aerocort Inhaler description
Aerocort Inhaler pharmacokinetics
Aerocort Inhaler (Levosalbutamol, Beclomethasone) is indicated in the treatment of asthma, once the need for inhaled corticosteroid and bronchodilator therapy has been established.
DOSAGE AND ADMINISTRATION
Aerocort Inhaler (Levalbuterol / Levosalbutamol, Beclomethasone) may be used with a Zerostat VT Spacer device by patients who find it difficult to synchronize aeros
ol actuation with inspiration of breath.
Two inhalations, three or four times daily, titrated to the lowest effective dose.
One or two inhalations, two, three or four times daily.
Hypersensitivity to any of the components of the formulation.
WARNINGS AND PRECAUTIONS
Aerocort Inhaler warnings and precautions
Levosalbutamol and non-selective beta-blocking drugs such as propranolol should not usually be prescribed together.
No interactions have been reported.
There is inadequate evidence of the safety of levosalbutamol in human pregnancy.
There is inadequate evidence of the safety of beclomethasone dipropionate in human pregnancy.
Plasma levels of levosalbutamol after inhalation of therapeutic doses are very low in humans, but it is not known whether levosalbutamol is excreted in human
No specific studies examining the transference of beclomethasone dipropionate into the milk of lactating animals have been performed.
As Aerocort Inhaler contain levosalbutamol and beclomethasone dipropionate, the type and severity of adverse reactions associated with each of the compounds may be expected.
Mild tremor and headache have been reported. Paradoxical bronchospasm, hypokalaemia, allergic reactions, tachycardia dizziness and muscle cramps may occur.
Candidiasis of the mouth and throat (thrush), hypersensitivity reactions, easy bruising of the skin, adrenal suppression, growth retardation in children and
adolescents, hoarseness and throat irritation are common.
Very rare include Cushing's syndrome, decrease in bone mineral density, cataract, glaucoma, and paradoxical bronchospasm.
The expected symptoms of overdosage are those of excessive beta-adrenergic stimulation, viz., seizures, angina, hypertension or hypotension, tachycardia (with
rates up to 200 beats / min), arrhythmias, nervousness, and fatigue. Cardiac arrest and, even, death is associated with the abuse of levosalbutamol.
If higher than recommended dosage is continued over prolonged periods, some degree of adrenal suppression may result. Monitoring of adrenal reserve may be necessary. In cases of beclomethasone dipropionate overdose, therapy may still be continued at a suitable dosage for symptom control.
Levosalbutamol, Beclomethasone (Aerocort Inhaler) canister containing 200 metered doses
Manufactured and distributed by Cipla pharmaceutical company and its divisions.
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